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Children born to older women may be defective.

1. At birth, the female ovary contains approximately 2-4 million eggs. After birth, new eggs are not added.
2. Out of this eggs, only about 400 are destined to be ovulated, while all others degenerate during development, so that only a few remain by the age of 50.
3. Thus, eggs ovulated near the age of 50 are 30-40 years older than those ovulated just after puberty.
4. This ageing of eggs can cause defects in the children born to older women.